Liquid Dose Manufacturing

Prefilled Syringe Plungers: Mitigate Against Risks To Improve Success

From start to finish, NovaPure components have been designed and manufactured using Quality by Design principles to mitigate risk for the patient.

How Oral GLP-1 Therapies Are Revolutionizing Obesity Treatment

The rising incidence and severity of obesity have amplified a therapeutic need in healthcare. Read more about Dr. Srinivasan Shanmugam discussing the challenges and impact of GLP-1 analogs.

Signant Health, formerly CRF Bracket

The best technology succeeds in the background. Signant Health provides solutions that simplify every step of the patient journey to make it easier for people to participate in, and for sites and study teams to run, clinical trials.

Integrity Bio

Provide help to those who strive to save or improve the quality of human life by providing them the integrated services of Formulation Development, GMP Fill Finish Services, and Innovative Drug Delivery technologies.

Haupt Pharma AG

With nine sites in Germany, Italy, France and Japan, and a representative office in the U.S., Haupt Pharma is one of the largest European companies for pharmaceutical contract development and manufacturing.

Kemwell Biopharma

With manufacturing locations in Bangalore India, and Uppsala Sweden, Kemwell offers the entire value chain from early & late stage drug development services, clinical trial supply support, to commercial contract drug manufacturing.

Laureate Pharma

Laureate Biopharma is a leader in biopharmaceutical contract development and manufacturing. Our scientists are expert in process development and cGMP production of therapeutic proteins, including monoclonal antibodies and Fc-fusion proteins.

Pharmaceutical Contract Manufacturing And Packaging: Creams, Lotions And Gels

Aphena Health & Beauty has the ability to blend a wide range of viscosities from aqueous based to crèmes, lotions, liquids, gels and powders. 

ADMET-PK and Bioanalytical Services The ADMET-PK Team at SCYNEXIS understands the challenges in optimizing the bioavailability of a molecule and is well-equipped to determine compound adsorption, distribution and metabolism with state-of-the-art instrumentation and techniques. They are fully-integrated in our efforts to provide fast and efficient medicinal chemistry decision support for rapid hit seeking, H2L, lead optimization and candidate selection. Lead optimization projects are guided by a portfolio of in vitro DMPK assays including plasma stability studies, cytochrome P450 inhibition assays and metabolite identification leading to in vivo animal studies to determine PK parameters. We offer fully-integrated contract research, discovery and development services including Drug Discovery, ADMET-PK, Bioanalysis and Process Chemistry & GMP API manufacturing.

Success with SCYNEXIS
Our team works in state-of-the-art facilities with access to a comprehensive suite of high-end biological assays and bioanalytical instrumentation. We have successfully developed and delivered numerous assays to our clients’ drug discovery and development programs including:

• CNS/brain tissue exposure for Stage II Human African Trypanosomiasis (HAT)
• Ocular tissue distribution of novel drug candidates for dry eye indications
• Prodrug and parent monitoring to improve bioavailability and release profiles

In Vitro ADMET Capabilities

Rodent & Large Animal PK Allometry Routes of Elimination	Tissue/CNS Distribution PK-PD Metabolite Profiling

Bioanalytical Capabilities

Method Development Sample Preparation Tissue Extractions Microtiter and Online SPE Metabolite ID Liquid Handlers

PK Screening Tandem-MS (MRM and SRM) Triple-Quadrupole MS HTS Platforms (Beckman, Tecan, LEAP) Prodrug Studies PD Studies