Newsletter | June 17, 2026

06.17.26 -- What's Slowing Your Cell & Gene Therapy Program?

Construct Viability: A Hidden Challenge In Viral Vector Manufacturing

Rapid, low‑cost checks can catch construct issues that limit vector manufacturing, enabling early fixes to improve titers, avoid delays, and accelerate gene therapy programs.

 

12.5x Titer Boost Accelerates CAR-T Program To IND Filing

Plasmid engineering and process development boosted viral titer 12.5×, eliminating manufacturing bottlenecks and enabling an on‑time regulatory submission for the cell therapy program.

 

Key Selection Criteria For Cell & Gene Therapy CDMOs

Choosing the right CDMO requires early internal assessment plus strong technical capability, agility, advocacy, clear communication, and long‑term alignment to meet evolving cell and gene therapy needs.

 

Improving LVV And AAV Yield Through Cargo Gene Silencing

Silencing cargo gene expression during LVV and AAV production improves cell health, reduces impurities, and significantly increases vector yield for cytotoxic and difficult‑to‑manufacture transgenes.

 

OPCU VIDEO FEATURE

Powering The Next Wave Of Cell And Gene Therapy Success

Minaris is a specialized global CDMO, offering end-to-end development, manufacturing, and testing services with over 25 years of expertise and personalized client support.