Two Decades, One Focus: Sterile Manufacturing Excellence

Afton Scientific, located in Charlottesville, Virginia, offers over 20 years of sterile manufacturing excellence, providing end-to-end aseptic fill-finish solutions for clinical and commercial injectable products. Known for their hands-on, communicative approach, Afton partners closely with clients to ensure product safety, compliance, and efficient project execution.

Their capabilities include clinical and commercial batch manufacturing of sterile injectables in vial sizes ranging from 2 mL to 100 mL, with batch yields of up to 97% and batch sizes reaching 20,000 units. Services include terminal sterilization, engineering batches, tech transfer, validation support, and Quality-by-Design (QbD) methodology. Looking ahead, Afton plans to expand capabilities by 2026 with an isolator filling line supporting vials, pre-filled syringes (PFS), and cartridges, with batch capacities up to 230,000 units.

Beyond manufacturing, Afton provides comprehensive support services such as custom clinical labeling, commercial labeling and packaging, kit assembly, serialization and aggregation, and flexible cold-chain storage with continuous monitoring. Their labs are equipped for advanced analytical and microbial testing and robust stability programs to ensure regulatory compliance and product confidence.

Clients praise Afton for quality products, attention to detail, fast regulatory turnaround, and a collaborative culture driven by senior staff engagement. Whether you're transferring your first technology or scaling a commercial product, Afton’s flexible and responsive model makes them a trusted partner in sterile manufacturing.