Newsletter | December 2, 2025

12.02.25 -- Solve High-Viscosity Challenges: Predictive Modeling Approaches & Data-Driven Insights

Predictive Modeling Of Viscosity Behavior Using Artificial Neural Networks

Review a modeling approach employing ANNs using experimental factors combined with simulation-derived parameters plus viscosity data from 27 highly concentrated (180 mg/ mL) mAbs. These ANNs can be used to predict if mAbs exhibit problematic viscosity at distinct concentrations or to model viscosity-concentration-curves.

A Smart, Data-Driven Approach To Formulate Biotherapeutics For PFS

Traditional injection force models often lack the accuracy needed for modern, high-viscosity formulations. Understand, through technical details and case studies, how accurate rheological data and syringe characterization enable better predictive models for injection force and ensure confident formulation for autoinjector success.

Empowering An Industry-Backed Method To Container Closure Integrity

In its continued dedication to being a leading outsourcing partner, Lonza collaborated with experts across the industry to detail a comprehensive science- and risk-based approach to CCI for parenteral combination products, which is now built into Lonza practices throughout its development and manufacturing network.

OPCU VIDEO FEATURE

Expertise And Advanced Technologies For Drug Product Manufacturing

Gain insights into new, large-scale drug product manufacturing expansions supporting vials, prefilled syringes, and highly potent antibody-drug conjugates. See how integrated development and supply services accelerate complex biologic therapies.