Product/Service

Safety Pharmacology Services

Source: Charles River

Charles River has established ICH core battery tests and supplementary safety pharmacology models to meet current regulatory requirements and provide meaningful data to accurately drive your decision-making process.

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Our safety pharmacology facilities feature dedicated telemetry suites, surgical capabilities and custom-built cardiovascular laboratories with remote observation of the animals without disrupting data collection. We have validated the use of electrocardiogram (ECG) pattern recognition software to increase the sensitivity of our ECG analyses.

ICH Core Battery Tests

  • Cardiovascular system
  • Respiratory system
  • Central nervous system (CNS)
  • hERG

Supplemental Studies

  • Tier II cardiovascular, CNS and respiratory assessments
  • Renal
  • Gastrointestinal