Overcoming Barriers To Patient Adherence With A Novel Dosage Form

Patients with neurological conditions often face physical barriers to medication adherence, particularly when tremors or dysphagia make swallowing capsules difficult or unsafe. To address this, a mid-sized pharmaceutical company partnered with formulation experts to develop a sprinkle version of their existing drug. The result: oral granules that can be mixed into soft food or liquids, offering a safer and more manageable alternative for patients and caregivers alike.

The innovation extended beyond formulation. A new manufacturing method was created to reinforce the granules’ structure, ensuring they remained intact through taste-masking and production processes. This advancement not only solved a key challenge for this product but also laid groundwork for future microencapsulation efforts.

FDA approval was secured in Spring 2024, and the product is now available in North America, with clinical trials underway to expand access globally. The sprinkle format has already shown promise in improving patient comfort, reducing caregiver stress, and supporting consistent medication use.

For teams focused on patient-centric solutions and formulation innovation, this case offers valuable insight into how dosage form design can directly impact quality of life. Explore the full asset to learn how formulation strategy and manufacturing ingenuity came together to solve a real-world adherence challenge.