Article | November 11, 2024

Optimizing Tablets For Even Splitting: The Pressure Sensitive Bisect Design

GettyImages-1669461851 tablet manufacturing

The pressure-sensitive bisect design offers the most effective tablet splitting, requiring patients to press the tablet bisect-down on a flat surface. The bisect is placed only on the upper punch, with depth carefully adjusted to maintain tablet strength. A 90° phi angle is standard, while maximizing facet width through a larger theta angle improves split ease. Facets can be flat or slightly curved for film-coating compatibility.

Sharp stroke radius improves splitting accuracy, while the break radius, ideally 68.28% of bisect depth, minimizes picking. A blend radius (min 0.015”) ensures tool strength. Each element works to provide accurate, patient-friendly dosage administration.

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Natoli Engineering Company, Inc.