Material Science Solutions

Aragen Life Sciences is India’s leading CRO, offering cutting-edge OLED (Organic Light Emitting Diodes) chemistry services, and has an impressive track record of collaborating with global leaders. Our expert material science team possesses the skills and experience necessary to deliver top-tier electronic-grade compounds for a range of applications in OLEDs, Printed Electronics (PE), Nanomaterials, and Biomaterials, establishing our position as the industry leader in this field.

Chemistry and Technologies

Synthesis – Expertise in handling diverse chemistry
Purification – Column Chromatography, Precipitation, Crystallization, and Sublimation

Characterization

• Compound characterisation with HPLC/UPLC, LCMS/HRMS, NMR etc.
• Method development, validation, and documentation as per ICH Q2R1
• Elemental impurities as per ICH Q3D
• Chiral method development (HPLC/GC/SFC)
• Impurity identification, characterization, and synthesis
• GPC (Gel permeation chromatography)
• Cleaning method development and validation

High purity organic compounds for OLED and PE – Typical specifications include high purity > 99.5%, ppm levels of residual metal contents, very low levels of residual solvent content, total inorganic content residual solvent content, physical appearance (color/solid), and UV profile

Reaction capabilities (R&D to pilot scale) – Fluorination, Pressure reaction (Parallel screening autoclave; SS316, PTFE, and Hastelloy), Cyanation, Boron chemistry, Cross-coupling reactions C-C, C-N, C-S, C-P, C-SI and C-H activation, Photochemical/Photo-redox reactions, and Amoco oxidation & Continuous flow/photo-flow chemistry.

Value Proposition

• Multi-year Collaboration with the world’s largest chemical companies
• Over 10+ years of experience to support discovery, development, and pilot-scale synthesis of electronic-grade compounds
• Scale-up lab to support large-scale synthesis (500 g to kg scale)

Infrastructure

• Triple jacketed reactors (Capacity – 250 mL to 20L)
• Reactor-Ready® (-70 to +200 °C), pH probe, and data log
• Catalyst screening using Radley Mya-4 equipment with a glove box
• Pressure catalyst screening (6 x 100mL capacity, SS316 and Hastelloy)
• Autoclaves (SS316 and Hastelloy) 450mL to 25L
• Par hydrogenators (Capacity – 200mL to 2000mL)
• Carousel 6 Plus and 12 Plus Reaction Station™ for quick optimization
• High temp (up to 250 °C) and high pressure (up to 80 bar) reactions
• Kugelrohr and sublimation apparatus
• Light-sensitive compounds up to 20L scale
• Non-Light Sensitive compounds capacity up to 3KL
• Photochemical Reaction (LED/UV) – capacity up to 2KLa