Article | October 30, 2025

Harnessing Digital Twins To Optimize Tablet Manufacturing

By Tony Beal

GettyImages-1276633131 digital twins

Digital twin technology, once primarily in aerospace and automotive, is fundamentally changing pharmaceutical manufacturing. Precision and predictability are critical in drug production, and virtual replicas of real-world systems are now being used to simulate, analyze, and optimize production environments with remarkable accuracy. This shift is already well underway, with market reports projecting significant growth and the majority of firms leveraging digital twins in R&D or process optimization projects.

This technology offers tangible benefits for manufacturers striving for higher quality and efficiency. By creating virtual models, teams can simulate production lines to identify bottlenecks, use real-time data to enable predictive maintenance and minimize costly downtime, and ensure enhanced quality control over parameters like tablet hardness and coating uniformity. While challenges remain in data integration and initial costs, digital twins are becoming essential for accelerating formulation scale-up, improving efficiency, and shortening time-to-market. Learn more about how this simulation-driven innovation is defining the future of solid dosage manufacturing.

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Natoli Engineering Company, Inc.