Article | January 25, 2024

Guidelines For Choosing The Right mAb Cell Line - Part 2

Scientists in Laboratory GettyImages-1199449498

Monoclonal antibodies (mAbs) are revolutionizing medicine, but their true potential hinges on a robust cell line. In the process of selecting a monoclonal antibody cell line, learn how a strategic approach to choosing the right cell line can ensure high-quality and consistent antibody production.

Focusing on selecting appropriate growth media and culture conditions is crucial to optimize antibody production. EirGenix uses proprietary expression vectors and signal peptides to enhance gene expression and reduce impurities. Single cell cloning is also employed to ensure monoclonality, and the stability of the cell line is crucial for long-term production.

Read the article to learn more about the importance of strategies such as high-throughput screening, parallel processing, and streamlined workflows in accelerating timelines and improving yield in cell line development. Optimizing expression vectors, generating new host cell lines, screening media, ensuring cell line stability, achieving monoclonality, and using easily scalable cell lines are all key considerations in this process.

Learn how a CDMO partner that addresses challenges in CHO cell line development and implements efficient and reliable solutions can enable the efficient production of biopharmaceuticals. EirGenix’s expertise in this field positions them as a leader in monoclonal antibody cell line development.

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