Product/Service

Gene Editing Services

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Choose from our different technology platforms or ask our scientists to customize a project to achieve your goals. We’ll use our patented and proprietary technologies, such as our Rapid Automated Cell Line Editing (RACE™) protocol, to ensure quality, accuracy, and fast turnaround times.

Capabilities

  • Knock-out 
  • Knock-in (up to 20 kb) 
  • Point mutation or single-base editing 
  • Complex, multi-step cell line engineering 
  • Footprint-free edits

Cell types* 

  • iPSCs (healthy or diseased) 
  • HEK293 
  • CHO 
  • Custom 
  • Research grade 
  • cGMP grade  
  • Matched research and cGMP grade 

Applications 

  • Disease modeling 
  • Tissue engineering 
  • Regenerative medicine R&D 
  • Therapeutic R&D 
  • Basic research 
  • Library construction 
  • Cell product cGMP manufacturing 

*We also offer CRISPR editing to generate rodent animal models — contact us to learn more.

With over 1,800 unique cell line models engineered by the scientist and technology developers at Applied StemCell, you can be confident in the quality and reliability of our service.  

  • Fast turnaround times—As quick as 6 – 8 weeks when you select one of the ASC control lines or master cell lines. Alternatively, send in your cells for a 2 – 3 month turnaround time.  
  • High success rates—Over 98% projects completed to our customer’s specifications 
  • Customizable deliverables—Choose homozygous mutations, heterozygous mutations, footprint-free genome editing (ideal for GMP applications), or other customization options 
  • iPSC engineering specialists—Pluripotency and genomic stability maintained throughout genome editing process  
  • Supply chain security—All projects completed at our facilities in California (cell-based projects) and Oklahoma (animal projects)