Brochure | June 13, 2025

Flow Chemistry Solutions

Source: Aragen
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There has been a recent paradigm shift from traditional batch manufacturing to continuous manufacturing, offering significant advantages in safety, efficiency, and process control. Continuous flow systems enable the safe handling of hazardous reactions such as nitration, azide chemistry, and halogenation. They also allow precise control of cryogenic reactions — including n-butyl lithium additions, DIBAL reductions, and Grignard reactions — at sub-zero temperatures.

Additionally, continuous manufacturing is well-suited for kinetically fast, toxic, or potentially runaway reactions where enhanced control is critical. It is also effective for high-temperature processes such as epimerizations and alkylations, as well as for conducting photochemical reactions in flow.

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