Newsletter | October 8, 2025

10.08.25 -- Execute Or Decay: Radiopharma's Outsourcing Reality

SPONSOR

Webinar: From First-in-Human to Proof-of-Concept — Quicker, Smarter, Streamlined

Unlock the keys to successful First-in-Human studies with Quotient. This webinar reveals how expert-designed SAD/MAD trials, flexible CMC strategies, and smart regulatory planning accelerate proof-of-concept while avoiding costly setbacks. Gain insider insights on biomarkers, patient recruitment, and data integration—plus real-world case studies across rare diseases, obesity, CNS, and inflammation. De-risk early development and keep your program moving forward. Click here to learn more.

INDUSTRY INSIGHTS

Layer By Layer: 3D Screen Printing And The Future Of Drug Development

3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.

Lower Punch Tip Bending And Buckling

When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.

FEATURED EDITORIAL

Execute Or Decay: Radiopharma's Outsourcing Reality

The radiopharmaceuticals industry is benefiting from increasing investments and a rush of promising innovation. At the same time, it faces a rather spotty outsourcing services and supply infrastructure. The Radiopharmaceutical Blueprint Report calls this the industry’s central paradox, “a multi-billion-dollar wave of investment and commercial validation is colliding with a fragile, underdeveloped infrastructure” of isotope supply, GMP manufacturing, and talent.

Advice For Managing Multiple CDMOs

We all look to simplify the supply chain. Unfortunately, simple (or even consolidated) isn't always possible. You are left with the heavy task of managing multiple CDMOs across a supply chain. At a recent Outsourced Pharma Live digital discussion, we learned how.

INDUSTRY INSIGHTS CONTINUED

Nanoformed API: A Superior Alternative To Solid Dispersions

Cutting-edge nanotechnology is now emerging, able to address bioavailability challenges and deliver higher drug loads in more patient-friendly formats with fewer and smaller pills and easier regimens.

The Power Of AI And Route Scouting To Navigate API Complexity

Using AI tools for retrosynthesis can help you investigate molecules interactively to build a complex API manufacturing process that maintains your timeline and saves you money.

Solving Delivery Challenges For Tolerogenic Vaccines

Explore the advantages offered by an orally dissolving tablet platform relating to large molecule storage, aggregation, and, in some cases, protease activity.

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Join 1,000+ pharma, biotech, and drug delivery professionals at the PODD: Partnership Opportunities in Drug Delivery Conference, October 27–28 in Boston. Featuring 10 technology tracks, pharma company spotlights, 1:1 partnering, and more. Attendees will also hear from leaders at companies including AbbVie, Amgen, AstraZeneca, Biogen, Eli Lilly, GSK, Moderna, Novartis, Pfizer, Regeneron, Roche, Sanofi, Takeda, and others. Register at PODDConference.com with code LSL20 for 20% off.

SOLUTIONS

Fill/Finish Capabilities Update January 2025

From early development through small-scale production to global commercialization, our experience with international agencies underscores our ability to navigate complex requirements with precision.

Sachet Packaging Solutions Catering Diverse Needs

Discover versatile, high-quality sachets for manufacturers and consumers with an ideal fill weight of 2 grams and above that is suitable for food or liquid formulas.

Fostering A Collaborative, Cross-Functional Approach

Our collaborative environment ensures efficient project execution and thorough product testing across multiple sites, consistently delivering client satisfaction.

OUTSOURCED PHARMA CAPACITY UPDATE

Find Your New CDMO At Outsourced Pharma Capacity Update

CDMOs in biologics, cell and gene, and small molecule share their capabilities and available capacities. See for yourself why this virtual event has become a wildly popular resource to identify options for your development and manufacturing needs.

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