Newsletter | September 10, 2025

09.10.25 -- Creating Better Biologics With Leap-In Transposase And Machine Learning

Cell Line Development For Bispecific Antibodies

See how the recently described cell line development paradigm shift, enabled by the Leap-In transposon platform, can extend to the development of bispecific monoclonal antibody-producing cell substrates.

 

An Alternative Genetic Engineering Tool In CHO Cells

Discover how transposon technology is being reimagined as a precise genetic engineering tool to create high-performing CHO cell lines for biotherapeutic production with enhanced metabolic and glycan profiles.

 

Obtain Proteins With Optimal Properties For Commercial Applications

Explore a unique protein platform that relies on Design of Experiment (DoE) to calculate the set of nodes that are maximally information-rich in the relevant space, gene synthesis to make those exact sequence nodes, high quality measurements to quantify function, and machine learning to find the optimal solution.

 

Using GPS Engineering To Optimize Antibody-Based Drug Development

A platform has been developed using ML-guided GPS Engineering to optimize the development of antibody-based drugs. Examine how utilizing the platform impacts all stages of an antibody's life cycle, from discovery to manufacturing.

 

Build Better BioTherapeutics Using Machine Learning And Synthetic Biology

Explore ATUM's history with Machine Learning (ML) in Bio, as well as how they go about variable selection, searching the SQL space to find promoters, and finding antibodies.