Beyond Solid Phase Synthesis

The rapid expansion of complex TIDES therapeutics is pushing development teams to rethink traditional solid‑phase synthesis methods. As sequences grow longer and quality expectations tighten, new tools are emerging to ease bottlenecks in efficiency, control, and sustainability. Enzymatic ligation, advanced process analytical technology (PAT), and AI‑powered optimization are creating fresh opportunities to scale long-sequence synthesis with greater confidence.

This webinar brings together scientific and process experts to examine how these integrated approaches are reshaping modern TIDES development. Attendees will gain practical insight into how enzymatic strategies can support extended sequences while reducing resource demands, and how real‑time analytics enable earlier detection of variability during scale-up. The session also explores how data-driven process design — supported by AI — can help teams accelerate development timelines without compromising purity, yield, or consistency.

For anyone navigating the challenges of long-sequence peptide and oligonucleotide production, this discussion offers actionable strategies to modernize workflows and strengthen process robustness.