Applications Of Liquid-Filled Hard-Shell Capsules In Drug Development

Liquid-filled hard-shell capsules (LFHCs) serve as a favored formulation for oral solid delivery of chemical drugs and nutraceuticals, particularly beneficial for substances with limited solubility and bioavailability. Beyond addressing these challenges, LFHCs find diverse applications, showcasing specific advantages in early-phase clinical development.

Explored in this edition of The Altascientist are the various applications of LFHCs, the formulation development process, the pivotal role of excipients, and additional benefits associated with LFHCs. A detailed case study is also presented, highlighting the swift development of an LFHC formulation for Cannabidiol, offering practical insights into the successful application of this approach. This comprehensive exploration underscores the versatility and significance of LFHCs in pharmaceutical and nutraceutical delivery, shedding light on their role in enhancing drug solubility, bioavailability, and overall efficiency, with a particular focus on their rapid development in the case of specific compounds like Cannabidiol.