A Hybrid Approach For Optimizing Transient Protein Expression In CHO Cells

By James Harvey, Shlomit Segev, Maya Wadmany, Peter O’Callaghan, Frida Grynspan, Bernadette Sweeney

When choosing between protein expression formats such as transient versus stable pools, considerations include speed, cost, titre, and product quality.

GS Discovery® is a novel, scalable, transient expression solution driving high titers that rival those of leading off-the-shelf kits. As part of the GS System®, GS Discovery® enables you to use the same tools (cell lines, vectors, and GS piggyBac® transposon technology) from discovery through to commercial production. This supports robust product quality attributes and streamlined development.