Outsourced Pharma App Notes & Case Studies
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Optimizing And Scaling Lentiviral Vector Production
10/23/2023
Here, we outline how the upstream and downstream workflows of the VirusExpress® platform for lentiviral vectors were optimized through the use of design of experiments and supplementary studies.
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Applying A Platform Approach To Bispecific Antibody Development
6/16/2023
Explore how experts were able to adjust a mAb production and purification platform to be applicable for the rapid development and scale up of a BsAb.
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Process Control And Performance Of A Virus Filtration System
1/12/2023
Discover a single-use automated filtration system designed to deliver robust process control and integrity assurance during the critical purification step. Explore its design features, processing control, and more.
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AAV Production In Suspension HEK293 Cells With Single-Use Bioreactors
10/13/2022
Explore how we expanded HEK293/HEK293T suspension cells from small cell culture (20 mL) in shake flasks up to a 10 L culture in a benchtop Xcellerex™ XDR-10 single-use bioreactor system.
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COVID-19 Impact To Biological Drug Products Safety
6/13/2022
Review currently available literature and our recommended COVID-19 virus detection test methods and susceptibility of common biological host cells to infection.
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Understanding The Microfluidic Platforms For Scaling Nanoparticle Production
10/13/2022
Learn about the benefits of microfluidics for nanoparticle production over traditional methods as well as scaling nanoparticle production for clinical or industrial use.
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Accelerating Treg Therapy Manufacturing
8/15/2023
Learn more about the strategies that helped accelerate the development timeline and build a process to isolate, engineer, and expand mature, thymic Tregs.
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Get Full Control Of Your T Cell Isolation
3/25/2024
This study demonstrates the automated magnetic isolation of CD4/CD8+ cells from fresh or frozen leukapheresis using a functionally closed cell processing system paired with a modular application.
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Trends In Next-Generation Delivery Technologies
11/22/2023
Learn how lipid nanoparticles are enabling a new generation of engineered cell therapies with a push toward more complex cell engineering and gene editing for allogeneic therapies.
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Development Of A Novel Cell Culture Medium For AAV Production
9/26/2023
Explore the medium development process of a novel cell culture medium for AAV production with multiple HEK293 lineages, which was performed with three different HEK293 cell lines to maximize AAV titers.