Outsourced Pharma App Notes & Case Studies
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Generating A Robust Host Cell Line For A Cell Line Development Platform
11/14/2022
Learn how cell performance within the context of the cell line development workflow was confirmed with the successful isolation of stable, high-producing clones from three model monoclonal antibodies.
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rAAV Production Using HEK293 Cell Line And Transfection Medium
1/13/2023
Investigate how using a peak expression cell culture medium in the right bioreactor can promote recombinant protein production and improve the performance of a scalable AAV process.
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Risk Mitigation Through Dual Sourcing Strategy
8/22/2022
A global biopharmaceutical company with a high value, highly potent drug product for a rare disease indication approached a CDMO to secure supply for a life-changing commercial drug product.
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Understanding The Microfluidic Platforms For Scaling Nanoparticle Production
10/13/2022
Learn about the benefits of microfluidics for nanoparticle production over traditional methods as well as scaling nanoparticle production for clinical or industrial use.
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Recombinant Adeno-Associated Virus Type 5 Production Process
10/12/2022
Learn about a scalable process for the production of rAAV using triple plasmid transfection of suspension cells in an animal-derived component-free medium.
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Overcoming Supply Chain Roadblocks To Ensure Reliable Complex OSD Delivery
2/26/2024
Ensuring critical oral solid dosage (OSD) therapeutics reach patients successfully relies on the ability of developers and manufacturers to navigate the inherent issues surrounding their increasing complexity.
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Exosome Isolation By TFF And Size Exclusion Chromatography
3/6/2024
Here, we demonstrate a scalable workflow for the isolation of exosomes that combines tangential flow filtration for the concentration of exosomes followed by gentle size exclusion chromatography.
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Biacoreā¢ SPR Systems For Titer Analysis Of Adeno-Associated Virus
10/13/2022
We describe the performance of two assays for titer analysis of adeno-associated virus (AAV), serotype 2 and serotype 5, based on surface plasmon resonance (SPR).
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Improving An Abandoned Cancer Medication Using Innovative ASD Technology
3/1/2024
Review the case study and learn how KinetiSol Solid Dispersion lowered patients' pill burdens and demonstrated an improved therapeutic response for Galeterone.
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Recombinant Protein Purification Optimization With HIC
5/1/2023
A step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).