Article | October 2, 2015

Trehalose: A Powerful Excipient In The Formulation Toolbox

Source: Pfanstiehl, Inc.

By Ben Nelson, PhD, and Chris Wilcox

Trehalose is a non-reducing disaccharide consisting of two glucose molecules linked by an α,α–1,1 glycosidic bond. In the pharmaceutical industry, products which benefit from the stabilizing effects of trehalose include, but are not limited to: monoclonal antibodies (mAbs), antibody drug conjugates (ADCs), fusion proteins, peptides, stem cells, and vaccines.

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