Drug Discovery Whitepaper and Articles
-
Potent Rifampicin Derivatives Can Clear MRSA Infections At Single Low Doses When Concomitantly Dosed With Vancomycin
1/4/2024
Multidrug-resistant bacteria are rendering antibiotics ineffective. Review preclinical results of a potent macrocycle derivative and why collaboration is crucial to transition discoveries into treatments.
-
The MAPPs Assay: A Useful Tool For The Assessment Of Immunogenicity
1/4/2024
Explore how MAPPS demonstrates promise as a valuable tool for comprehensive immunogenicity assessment in therapeutic protein development, contributing to safer and more effective biologics.
-
Considerations And Strategies For Hiring Biopharma Consultants
12/8/2023
Most organizations do not have the budget or workload to justify a team spanning all possible subspecialties. So, those gaps typically are filled with consultants who add clear value to delivering products and services for the company’s clients. But how do you find the right consultants?
-
PBPK Modeling For Optimized Controlled Release Formulation Development
8/24/2023
Examine the benefits of controlled release, the application of PBPK modeling in controlled release formulation development, and how modified release products can be developed to deliver optimal patient outcomes.
-
Recommendations For Successful IND Approval Of RNA-LNP Drugs
8/22/2023
The existing regulatory system is ambiguous for RNA therapeutics. Leverage this Investigational New Drug (IND) guide to help accelerate and strengthen the process IND filing of novel nanomedicines.
-
De-Risking Preclinical Candidates With Predictive Immunotoxicology
8/14/2023
From target engagement and mechanism of action to efficacy and prediction of adverse immune reactions, immunology assays deliver data that reduce your risk of failing later.
-
Nonrodent Models: Minipig Specialty Capabilities
6/1/2023
The minipig's similarity to humans, availability, known disease status, and feasibility of genetic manipulation offer advantages over traditional species, impacting ethical considerations and cost of animals in biomedical research.
-
Streamlining The Importing & Exporting Of Biological Samples
4/5/2023
Create a seamless and predictable import and export process by working with experienced bioanalytical laboratory partners, understanding what paperwork samples require, and proactive planning.
-
Validated HPLC-UV Method For Quantification Of Paxalisib
1/18/2023
Examine research into the development and validation of a HPLC method for the quantitation of paxalisib in mouse plasma and its potential use for routine therapeutic drug monitoring.
-
Validated LC–MS/MS Method For The Determination Of Copanlisib
11/14/2022
Review study findings on a validated LC–MS/MS method for quantifying copanlisib from a mouse dried blood spot and its potential for enabling desirable sensitivity, accuracy, and precision.