Articles

  1. Overcoming Food Effects, Variability, Solubility For A Non-Opioid Analgesic With Lipid-Based Formulations 3/20/2026

    Develop optimized lipid-based formulations to overcome solubility, stability, and food-effect challenges, enabling high-dose oral delivery and rapid progression to Phase 1 trials.

  2. Overcoming API Constraints And Tight Timelines With On-Demand Manufacturing 3/20/2026

    Use innovative lipid-based formulations and on-demand manufacturing to accelerate Phase 1 trials, enable flexible dose escalation, and maximize limited API for poorly soluble compounds.

  3. Solving Bioavailability Challenges In bRo5 Drugs 3/20/2026

    Leverage mechanistic, material-sparing formulation strategies to enhance bioavailability and accelerate development of challenging bRo5 small molecules, even with limited resources.

  4. Leveraging Softgel To Extend Vinorelbine's Lifecycle, Improve Patient Convenience 3/20/2026

    Develop innovative oral formulations of traditionally intravenous therapies to enhance patient convenience, ensure consistent systemic exposure, and support long-term brand value and market differentiation.

  5. Biocapacitance Measurement: A PAT Tool For Biomass Measurement In An Upstream Process 3/20/2026

    Leverage process analytical technologies (PAT) to gain real-time insight into product quality, strengthen control strategies, and build more efficient, scalable manufacturing processes for future success.

  6. A Cell Line Development Platform Accelerating Timelines To Clinic 3/20/2026

    To support a seamless transition from early clinical studies through to commercial manufacturing, cell line expression systems must be carefully designed and selected based on several critical attributes.

  7. Continuous Flow — An Emerging Alternative 3/17/2026

    Gain insights on transitioning from batch to continuous flow processes, the benefits of continuous flow chemistry, and ensuring regulatory compliance with Quality by Design (QbD) principles.

  8. Flow Chemistry Manufacturing: Support Across The Development Continuum 3/17/2026

    Unlock increased safety, yield, and sustainability in chemical processes. Discover how flow chemistry and custom reactor design handle challenging reactions from lab to large-scale manufacturing.

  9. Patented Process For Intermediates Useful For Etrasimod Arginine 3/13/2026

    Explore how rethinking the synthetic strategy for Etrasimod can overcome the limitations of legacy routes, enabling more efficient chirality control, improved scalability, and more practical industrial API production.

  10. Enhancing Drug Performance Through Lipid-Based Formulations For CNS Indication 3/11/2026

    Advance CNS-penetrant therapies by optimizing oral formulations to improve bioavailability, stabilize the API, and deliver more consistent and reliable drug exposure.