To Err Is Human, To Correctly Formulate Is Divine: Risky Assumptions For Addressing Limited Bioavailability

Increasing the bioavailability of a poorly soluble drug is a challenging aspect of the drug formulation and development process. Despite best efforts, formulation challenges still need to be overcome.

An estimated 70-90% of molecules experience solubility and bioavailability challenges¹. Some of these challenges are minor, while others are significant, and can even be detrimental to the successful clinical outcomes and eventual launch of your molecule. How can we best cope with these setbacks?

First, we must recognize and accept bioavailability challenges as an inherent part of the drug development process. Secondly, we must address some common assumptions made during the development stage that can have serious impacts on the timeline and cost of your project.

This eBook is designed to address some risky assumptions surrounding bioavailability issues during development and key ideas to consider for addressing them.