The Future Of Small And Large Molecule Bioanalytics Today

Traditional mass spectrometry and liquid chromatography have formed the backbone of bioanalytic techniques for small molecules, whereas ligand binding assays have been the backbone for large molecules over the past half century of drug development. As biologic therapies become more common, new analytic approaches have emerged to facilitate the analysis of larger and more complex substances. To truly understand the way these novel therapies function in living biological systems, however, a new dimension of study will be indispensable: spatial bioanalysis. This futuristic analytic technique provides answers regarding molecule function and form that—together with other state-of-the-art analytics— dramatically improves the quantity and quality of information obtainable in drug development studies.