Newsletter | September 16, 2020

09.16.20 -- Shedding Light On Outsourcing Shadows

From The Editor
Featured Editorial
Industry Insights
Evolution Of Sequencing Technology For Genomics Applications

Since 2003, after the completion of the Human Genome Project, significant progress has been made in sequencing. Learn how sequencing technologies have revealed astonishing data for multiple species.

How To Minimize Production Downtime By Maintaining Your Tablet Compression Tooling

Optimizing and maintaining tablet compression tooling surely brings challenges. Poorly performing tools are a challenge all pharmaceutical manufacturers must conquer. This blog reviews how to reduce common compression issues during production and eliminate tooling downtime and offers tips on how to extend the life of your tablet compression tooling.

Manufacturing Of Sterile Aqueous Suspensions: A Primer

Sterile suspensions are particularly difficult to manufacture. This technical article covers factors for success, including particle size, vehicle formulation, and considerations for high-shear mixing. 

The Evolution Of Supply Chain Security: Increased Focus On Raw Material Variability

Qualifying two suppliers, increasing capacity, implementing a scorecard methodology for strategic suppliers, and surveying suppliers for their number of production lines are all important ways to guarantee a steady supply of materials and technologies — but close attention must also be paid to raw materials.

Critical Factors Of Fill/Finish Manufacturing For Large Molecules

Large molecules require special handling procedures for bulk drug substance, formulation, and sterile filtering and filling of the final drug product, forcing change on many levels of the manufacturing process.

Breaking The Either-Or Paradigm Of CDMO Selection
Choosing a contract development and manufacturing organization (CDMO) often requires “either-or” tradeoffs that divide the candidate companies into polarities of size, location, and services offered. Yet a few CDMOs defy such predictable categorization — making them the ideal choice for biotech and pharma companies seeking a partnership beyond the status quo.
Trends And Challenges In Outsourced Oral Solid Dosage Forms

As drug companies have fewer and fewer new compounds entering their R&D pipelines the outsourcing of development and manufacturing activities for oral solid dosage forms and sterile forms is on the rise.

Managing Your CDMOs: Advice From Professionals Who Have Been On Both Sides Of Outsourcing

In case you missed it, our latest OP-Virtual is available On-Demand. Get advice and best practices from professionals who have had careers at both CDMOs and biotechs.