Product/Service

Preformulation CDMO Services

Source: CoreRx

Characterization of the Active Pharmaceutical Ingredient (API) is critical to designing a successful formulation approach.  CoreRx can evaluate the characteristics of your API, conduct small scale studies to understand key parameters around solubility and stability, and perform excipient compatibility studies to identify the right ingredients to enhance your APIs performance across a variety of dosage forms.  Further, CoreRx has brought on-board various technologies to control and reduce particle size, which among other things, can greatly enhance the bioavailability of your compound.

Preformulation Services include:

  • API Physical & Chemical Characterization
  • pH/Solubility Profile
  • Partition Coefficient
  • Thermal Analysis
  • Hygroscopicity Evaluation
  • Chemical & Physical Stability Evaluations

Particle Size Control & Reduction Technologies:

  • Jet Mill (Dry Process)
    – Particle size range of 1 – 45 microns
  • Microfluidization (Wet Process)
    – Particle size reduction for submicron and nano-sized particles
  • Proprietary MicroJetReactor (MJR®), Nanosizer (Wet Process)
    – Extreme particle size reduction for nano-sized particles down to 100nm