Newsletter | November 17, 2023

11.17.23 -- "Organizational Outsourcing" For Small Molecules


"Organizational Outsourcing" At Astex Pharmaceuticals

After decades working at CDMOs, Matthew Johnson decided to give it a go directly pushing along NCEs at a biopharma. The company he selected for this new endeavor has an interesting organizational matrix — components of an international, external-internal supply chain.

Best Practices For Use Of Risk Registers In Biopharmaceutical Manufacturing Operations

Risk registers can be a valuable risk management tool, and having a risk register is increasingly becoming a regulatory expectation. It can be structured as a database or spreadsheet and ensures decision makers have key information about risks. Discussion also includes pitfalls to avoid.


Engineering Approaches To Respiratory Drug Delivery

This article presents a case study that explores the material and performance properties of spray-dried and jet-milled mannitol for respiratory delivery of crystalline mannitol.

Maintaining Bioavailability And Masking Taste With Microencapsulation

Microencapsulation — wherein particles are co-formulated with polymers or other excipients to improve palatability, modify release rate, or enhance bioavailability — possesses advantages for many pharmaceutical applications.

5 Steps To Planning And Executing IND-Enabling Nonclinical Studies

Review five steps for planning and executing scientifically rigorous, compliant IND-enabling nonclinical studies to help move development programs forward.

How To Accelerate Your Molecule’s Pathway To IND And Beyond

Pharmaceutical companies and CDMOs are facing pressure to speed their timelines and reduce costs. Consider the challenges facing developers and how integrated approaches can help advance molecules to IND.


Quadrant 2®: Platform For Solubility And Bioavailability Enhancement

Quadrant 2 helps in early formulation development by employing in silico predictions of formulations via computational modeling analysis of your compound’s specific molecular structure and chemical characteristics.

API And Intermediates

Pfizer CentreOne has been delivering API and customer confidence for over 50 years. From farm to factory, raw ingredient to API, we can secure a safer supply chain, highest quality API, regulatory support, and transparent timelines.

Technology Transfer And Commercial Manufacturing Of Tablets And Capsules

Finding a strategic CDMO partner that will offer tailored solutions for your late-phase clinical and commercial needs, mitigate risks, and bolster your supply chain is crucial for meeting project milestones on time.


Find Your New CDMO At Outsourced Pharma Capacity Update

CDMOs in biologics, cell and gene, and small molecule share their capabilities and available capacities. See for yourself why this virtual event has become a wildly popular resource to identify options for your development and manufacturing needs.

Connect With Outsourced Pharma: