11.29.22 -- Enhancing Bioavailability: A Science-Based Technology Selection Process

Careful selection of the right technology to enhance bioavailability and oral drug absorption is essential in development programs from initial preclinical phases to commercialization. Explore a process based on a series of inputs including the target product profile, drug properties, extensive past project experiences, technology maps, and absorption modeling.

The increase in Breakthrough Therapy designations and other allowances for expedited regulatory review has led to ever more innovative drug products being developed under shortened timelines. How can companies navigate today’s regulatory environment while accelerating to clinical trials and commercialization?

Drug development programs are becoming more complex, often spanning global networks and multiple external providers or CDMOs. Even working with a single CDMO can require coordination between production sites located on different continents. Gain insights into the steps to streamline project management to benefit small and emerging biotech companies.

The combination of treatment strategies used for patients suffering from advanced cases of lung cancer can cause a wide range of side effects. Spray drying is a useful particle engineering technique that can deliver particles within the necessary specifications and can be used to manufacture locally delivered dry powder inhaler treatments.

Highly potent active pharmaceutical ingredients (HPAPIs) represent an increasing fraction of new compounds in pharmaceutical pipelines today. This presentation presents case studies demonstrating a range of solutions for HPAPI manufacturing, integrated drug substance and drug product development, and innovative business models.