Outsourced Pharma App Notes & Case Studies
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COVID-19 Impact To Biological Drug Products Safety
6/13/2022
Review currently available literature and our recommended COVID-19 virus detection test methods and susceptibility of common biological host cells to infection.
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Optimizing Recovery On The Sepax™ Cell Processing System
7/21/2022
Using a model T-cell line, we demonstrate the impact of varying rinse volume, intermediate volume, and manual extraction parameters on overall cell recovery with a final product dose volume of 20 mL.
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Development Of A Novel Cell Culture Medium For AAV Production
9/26/2023
Explore the medium development process of a novel cell culture medium for AAV production with multiple HEK293 lineages, which was performed with three different HEK293 cell lines to maximize AAV titers.
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Scalability And Performance Of Mobius® iFlex Bioreactors
1/19/2024
Utilizing single-use bioreactors in intensified fed-batch and perfusion processes can help manufacturers produce a high-quality drug supply while reducing facility footprint and production costs.
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Maximize Product Recovery In Bulk Filtration And Filling Flow Paths
12/15/2022
Explore a fill system designed to automate product draining and recovery within a batch to standardize processes and minimize non-recoverable hold-up within the filtration and distribution flow path sections.
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Product Manufacturing And Analytical Testing For An Ocular Client
1/8/2024
Unearth how Altascienes manages procurement logistics, manufactures the product, performs analytical testing, and terminally sterilizes it for final delivery.
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Solid-State Characterization Of A Small Molecule API
4/10/2024
Ensuring the consistency and purity of the API is paramount when developing a new drug. Learn about the importance of CRO partnerships when facing tight deadlines and complex scientific hurdles.
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Reducing The Level Of Host Cell Proteins In The Bioreactor Harvest
10/20/2023
Learn how MilliporeSigma helped a customer drastically reduce the level of HCPs in the bioreactor harvest prior to a production run to supply drug substance for a scheduled Phase 1 clinical trial.
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Transition To Closed Processing Systems For Cell Expansion And Banking
10/12/2022
Learn about one facility's transition to closed processes for the expansion of suspension CHO and Sf9 cells and how the closed system compares to traditional processing.
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Process Control And Performance Of A Virus Filtration System
1/12/2023
Discover a single-use automated filtration system designed to deliver robust process control and integrity assurance during the critical purification step. Explore its design features, processing control, and more.